Physical and chemical properties of dna pdf

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physical and chemical properties of dna pdf

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It is sometimes called the "molecule of heredity," because parents transmit copied portions of their own DNA to offspring during reproduction, and because they propagate their traits by doing so.

Rice mtDNA appeared in the electron microscope as a collection of linear molecules with heterogeneous length in the range of 1— kb. The major distribution area was 60— kb. Some molecules had the appearance of being supercoiled. Replication fork structures were found in both circular and linear mtDNA molecules.

DNA Molecule

Dawn B. Marks, Verne N. Schumaker; Some physical and chemical properties of trypsin-digested nucleoprotein. Biochem J 1 October ; 4 : — A series of trypsin-digested nucleoprotein preparations differing only in molecular weight were prepared by blending. The intrinsic viscosity and average sedimentation coefficient were determined for each of these preparations.

From a comparison of these results it was concluded that the presence of the complex-forming peptides causes a large decrease in intrinsic viscosity of the DNA and an increase in sedimentation coefficient.

In addition, the hydrodynamic data indicate that the DNA—peptide complex behaves like a coil in solution but is more compact than the same length of DNA. These findings suggest that the peptides are not strongly associated with the DNA, and that secondary valency forces are involved in the binding. Sign In or Create an Account. Advanced Search. Sign In. Skip Nav Destination Article Navigation. Close mobile search navigation Article navigation. Volume , Issue 4. Previous Article Next Article.

All Issues. Cover Image Cover Image. Article Navigation. Research Article October 01 Some physical and chemical properties of trypsin-digested nucleoprotein Dawn B. Marks ; Dawn B. This Site. Google Scholar. Verne N. Schumaker Verne N. Biochem J 4 : — Get Permissions. You do not currently have access to this content.

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Some physicochemical properties of rice mitochondrial DNA

Alongside proteins , lipids and complex carbohydrates polysaccharides , nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life. The two DNA strands are known as polynucleotides as they are composed of simpler monomeric units called nucleotides. The nucleotides are joined to one another in a chain by covalent bonds known as the phospho-diester linkage between the sugar of one nucleotide and the phosphate of the next, resulting in an alternating sugar-phosphate backbone. The nitrogenous bases of the two separate polynucleotide strands are bound together, according to base pairing rules A with T and C with G , with hydrogen bonds to make double-stranded DNA. The complementary nitrogenous bases are divided into two groups, pyrimidines and purines. In DNA, the pyrimidines are thymine and cytosine; the purines are adenine and guanine.

Mayor, S. Drake, L. This satellite virus DNA does not appear to differ in its physical, chemical and biological properties from DNA isolated directly from virions or from cells coinfected with adenovirus. The DNA is double-stranded with a buoyant density of 1. It sediments at 16S in both neutral and alkaline sucrose gradients.

Nucleic acid , naturally occurring chemical compound that is capable of being broken down to yield phosphoric acid , sugars, and a mixture of organic bases purines and pyrimidines. Nucleic acids are the main information-carrying molecules of the cell , and, by directing the process of protein synthesis , they determine the inherited characteristics of every living thing. DNA is the master blueprint for life and constitutes the genetic material in all free-living organisms and most viruses. RNA is the genetic material of certain viruses, but it is also found in all living cells, where it plays an important role in certain processes such as the making of proteins. Nucleic acids are naturally occurring chemical compounds that serve as the primary information-carrying molecules in cells.


Mechanical Properties of DNA. DNA is a biological polymer that has many unique physical and chemical proper-. ties and serves a critical and.


Nucleic acid

Alongside proteins , lipids and complex carbohydrates polysaccharides , nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life. The two DNA strands are known as polynucleotides as they are composed of simpler monomeric units called nucleotides. The nucleotides are joined to one another in a chain by covalent bonds known as the phospho-diester linkage between the sugar of one nucleotide and the phosphate of the next, resulting in an alternating sugar-phosphate backbone. The nitrogenous bases of the two separate polynucleotide strands are bound together, according to base pairing rules A with T and C with G , with hydrogen bonds to make double-stranded DNA. The complementary nitrogenous bases are divided into two groups, pyrimidines and purines.

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DNA Molecule

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Physical & Biochemical Properties of DNA and The Technology involve them.pdf

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